Analysis of potentially inappropriate medications in two cardiac intensive care units: a cross-sectional study
DOI:
https://doi.org/10.12957/reuerj.2024.83110Keywords:
Patient Safety, Aged, Cardiovascular Diseases, Drug Utilization, Potentially Inappropriate Medication ListAbstract
Objective: to analyze the association between the use of potentially inappropriate medications and the comorbidities of elderly patients hospitalized in cardiac intensive care units, with a focus on patient safety Method: observational cross-sectional study with a quantitative approach. Approved under ethical opinion number 4,503,135. The study settings were two coronary intensive care units in a university hospital in Rio de Janeiro. Data collection was documentary. Potentially inappropriate medications were classified based on the Beers Criteria®. Odds ratio and a p-value of less than 0.05 were used for association analysis. Results: data from 201 patients were analyzed, identifying 2,259 prescribed medications, with 369 (16.3%) being potentially inappropriate medications. Omeprazole was the most prevalent drug among prescriptions, with 145 (39.2%). Conclusion: hypertension was the comorbidity that showed a positive association with the use of potentially inappropriate medications (OR=1.6).
References
Gorzoni ML, Fabbri RMA, Pires SL. Potentially inappropriate medications in elderly. 2012 [cited 2022 May 22]; 58(4):442-6. DOI: https://doi.org/10.1590/S0104-42302012000400014.
World Health Organization. World Population Prospects 2022. WHO, 2022 [cited 2023 Apr 28]. Available from: https://population.un.org/wpp/Download/Standard/Population/.
Instituto Brasileiro de Geografia e Estatística (IBGE). Paises. IBGE, 2022 [cited 2022 Mar 27]. Available from: https://paises.ibge.gov.br/#/.
Santos Neto JM, Fernandes LG, Silva JO, Araujo JRS, Fraga GG, Barbosa AFC, et al. Análise da morbimortalidade por doenças infecciosas e parasitárias em idosos no brasil: uma avaliação retrospectiva de 2018 a 2023. REASE. 2024 [cited 2024 Aug de 21]; 10(6):2278-90. DOI: https://doi.org/10.51891/rease.v10i6.14534.
Ramos LR, Tavares NUL; Bertoldi AD, Farias MR, Oliveira MA, Luiza VL, et al. Polypharmacy and polymorbidity in older adults in Brazil: a public health challenge Rev. Saúde Pública. 2022 [cited 2023 May 21]; 50(Sup. 2):9s. DOI: https://doi.org/10.1590/S1518-8787.2016050006145.
Masoro EJ. Fisiologia do Envelhecimento. In: Martin D e Snyder A (Eds.). Livro de texto de medicina geriátrica e gerontologia. 8ed., Filadélfia; Elsevier Inc, 2019; p. 51.
American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2019 Updated AGS Beers Criteria® for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2019 [cited 2024 Aug 21]; 67(4):674-94. DOI: https://doi.org/10.1111/jgs.15767.
Gallagher P, Ryan C, Byrne S, Kennedy J, O'Mahony D. STOPP (Screening Tool of Older Person's Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation. Int J Clin Pharmacol Ther. 2008 [cited 2023 May 21]; 46(2):72-83. DOI: https://doi.org/10.5414/cpp46072.
Hagstrom K, Nailor M, Lindberg M, Hobbs L, Sobieraj DM. Association between potentially inappropriate medication use in elderly adults and hospital-related outcomes J Am Geriatr Soc. 2015 [cited 2023 Apr 03].63(1):185–6. DOI: https://doi.org/10.1111/jgs.13229.
Praxedes MFS, Pereira GCS M, Lima CFM, Santos DB, Berhends JS. Prescribing potentially inappropriate medications for the elderly according to Beers Criteria: systematic review. Ciênc. saúde coletiva. 2021 [cited 2023 May 21]; 26(8):3209-19. DOI: https://doi.org/10.1590/1413-81232021268.05672020.
Cuschieri S. The STROBE guidelines. Saudi J Anaesth. 2019. [cited 2024 Aug 21]; 13(Suppl 1):S31-4. DOI: https://doi.org/10.4103/sja.sja_543_18.
Barbosa DC, Ottaviani AC, Alves ES, Inouye K, Brito TRP, Santos-Orlandi AA. Relação entre apoio social e sono de pessoas idosas cuidadoras em vulnerabilidade social. Rev. enferm. UERJ. 2024 [cited 2024 Aug 21]; 32(1):e74486. DOI: https://doi.org/10.12957/reuerj.2024.74486.
Conselho Nacional de Saúde (Brasil). Resolução nº. 466, de 12 de dezembro de 2012. Conselho Nacional de Saúde, do Ministério da Saúde, que impõe revisões periódicas a ela, conforme necessidades nas áreas tecno científica e ética. Diário Oficial da União 12 dez 2012 [cited 2023 June 27]. Available from: https://conselho.saude.gov.br/resolucoes/2012/Reso466.pdf.
Procópio BG, Andrade LAC, Campos ACV. Perfil Farmacoterapêutico e uso de medicamentos potencialmente inadequados entre idosos em Marabá – PA. Saúde (Sta. Maria). 2021 [cited 2023 June 27]; 47(1):e42070. DOI: https://doi.org/10.5902/2236583442070.
Gorzoni ML, Rosa RF. Beers AGS 2019 criteria in very old hospitalized patients. Rev. Assoc. Med. Sutiãs. 2020. [cited 2023 June 27]; 66(7):918-23. DOI: https://doi.org/10.1590/1806-9282.66.7.918.
Santos TO, Nascimento MM, Nascimento YA, Oliveira GC, Martins UC, Silva DF, et al. Interações medicamentosas entre idosos acompanhados em serviço de gerenciamento da terapia medicamentosa da Atenção Primária. einstein (São Paulo). 2019 [cited 2023 June 27]; 17(4):eAO4725. DOI: https://dx.doi.org/10.31744/einstein_journal/2019AO.
Lima ED, Silva RG, Ricieri MC, Blatt CR. Farmácia clínica em ambiente hospitalar: enfoque no registro das atividades. Rev. Bras. Farm. Hosp. Serv. Saúde. 2018 [cited 2023 June 27]; 8(4):18-24. DOI: http://dx.doi.org/10.30968/rbfhss.2017.084.004.
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Flavia Giron Camerini, Isabelle Araujo da Silva Alves da Silva, Ana Lucia Cascardo Marins, Cintia Silva Fassarella, Danielle de Mendonça Henrique, Raquel de Mendonça Nepomuceno
This work is licensed under a Creative Commons Attribution 4.0 International License.
When publishing in Revista Enfermagem UERJ, the authors declare that the work is their exclusive authorship and therefore assume full responsibility for its content.
Authors retain copyright to their article and agree to license their work using a Creative Commons Attribution International Public License (CC BY), thereby accepting the terms and conditions of this license (https://creativecommons.org/licenses/by/4.0/legalcode.en), which allows material created by the author to be distributed, copied and displayed by third parties. The original work must be cited and present a link to the article available on the website of the journal in which it was published.
The Copyright of the articles published in Revista Enfermagem UERJ belongs to their respective author(s), with the rights of first publication assigned to Revista Enfermagem UERJ, with the work simultaneously licensed under a Creative Commons License CC BY, which allows sharing of work with recognition of authorship and initial publication in this journal.
The authors grant Revista Enfermagem UERJ the right of first publication, to identify themselves as the original publisher of the work and grant the magazine a license of non-exclusive rights to use the work in the following ways:
- Sell and/or distribute the work in printed copies and/or electronic format;
- Distribute parts and/or the work as a whole with the aim of promoting the magazine through the internet and other digital and printed media;
- Record and playback work in any format, including digital media.
In line with the journal's policies, each published article will be assigned a Creative Commons Attribution (CC BY) license.
