Evaluation of body composition and biochemistry of patients with chronic kidney disease undergoing non-dialysis treatment
DOI:
https://doi.org/10.12957/demetra.2022.63144Keywords:
Renal Insufficiency Chronic. Body Composition. Nutritional Status. Anthropometry.Abstract
Introduction: The study evaluated the body composition and biochemical tests of patients with chronic kidney disease (CKD) undergoing non-dialysis treatment. Method: Cross-sectional study including patients with CKD stages 3 to 5, older than 60 years (n=138). Body Mass Index (BMI), calf (CC), brachial (BC), brachial muscle (BMC), and waist circumferences (WC) and triceps skinfold thickness (TST) were evaluated. Through bioimpedance, it was obtained: lean tissue mass (LTM), LTM index, body cell mass (BCM), adipose tissue mass (ATM), ATM index, fat percentage, total body water (TBW), extracellular water (ECW) and intracellular water (ICW). Biochemical tests, such as blood glucose, lipid profile, uric acid, urea, creatinine, vitamin D, and minerals were evaluated. Descriptive analysis was performed according to sex and compared using Student's t, Mann-Whitney, and chi-square tests. Simple linear regression was performed to predict body composition and biochemical tests, according to glomerular filtration rate (GFR), adjusted for sex and age. Results: The prevalence of overweight was 70.4% in females and 53.7% in males. The percentage of fat was high in 90.7% of women and 91.7% of men. On the other hand, muscle mass depletion had a prevalence of 35.2% and 30.0%, respectively. Men presented higher values of BMC, BCM, LTM, LTM index, TBW, ECW and ICW. Women, presented higher values of BMI, PCT, body fat, ATM and ATM index. GFR correlated with serum urea (r2 = 0.279), potassium (r2 = 0.018) and HDL (r2 = 0.202). Conclusion: High prevalence of changes in body composition and biochemical tests were identified in patients with CKD undergoing non-dialysis treatment.
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