Biochemical effects of bacuri oil (Platonia insignis) in male mice
DOI:
https://doi.org/10.12957/demetra.2023.73360Abstract
Introduction: The utilization of medicinal plants as a source of therapeutic products has been a part of human history. Platonia insignis is a fruit species native to the eastern Amazon, popularly known as bacuri. The oil extracted from bacuri seeds provides a chemical composition with a high content of active substances with healing, antioxidant, and anti-inflammatory effects. Objective: This study aims to characterize the biochemical effects of bacuri oil as a possible preventive therapeutic alternative. Method: 15 adult Swiss mice were used, divided into three groups. Bacuri oil at doses of 10 and 100 mg/kg and the vehicle (olive oil – 10 ml/kg) were administered orally for 30 consecutive days. After 24 hours of administration of the natural compound and vehicle, the animals were euthanized; blood collected by cardiac puncture and plasma used to perform biochemical analyses. The biochemical parameters were evaluated: glucose, total cholesterol, LDL (Low Density Lipoprotein) and HDL (High Density Lipoprotein) cholesterol, triglycerides, glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), gamma glutamyl transferase (GGT), urea , creatinine, and total proteins. Results: Pretreatment with bacuri oil promoted beneficial effects on the biochemical parameters analyzed. Conclusions: In this way, the fruit can be used as a therapeutic alternative in the prevention of diseases.
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