VITAMIN D AND SELENIUM IN HASHIMOTO'S THYROIDITIS: BYSTANDERS OR PLAYERS?
DOI:
https://doi.org/10.12957/demetra.2018.30496Keywords:
Hashimoto Disease. Vitamin D. Selenium.Abstract
Objective:To investigate the scientific evidence of how vitamin D and selenium are related to serum levels of thyroid hormones,anti-TPOAb antibodies and enzymatic activity, as well as the effect of supplementation. Methodology: The study was carried out by using PubMed, Scopus and Web of Science databases, limited according to type of study (original articles and meta-analyses), language (English, Spanish and Portuguese) and publication time (last ten years). Results: Individuals with Hashimoto's thyroiditis have a higher prevalence of vitamin D deficiency (n= 11), which may contribute to the proliferation of antibodies, but it is unrelated to the hormones thyroxine and triiodothyronine. As for selenium, supplementation contributed to the reduction of antibodies (n=5) and improvement of the hormonal profile (n=6). Conclusion: Individuals with Hashimoto's thyroiditis have low serum levels of vitamin D and the supplementation of both calcitriol and selenium seem to be effective for the reduction of antibodies and improvement of the hormonal profile, but so far there is no convincing scientific evidence to support such practice.
DOI: 10.12957/demetra.2018.30496
Downloads
Downloads
Published
How to Cite
Issue
Section
License
STATEMENT OF AUTHORSHIP RESPONSIBILITY
Title of the manuscript:
________________________________________________________
1. Statement of responsability
I certify that I have participated in the work above specified and take public responsibility for its content.
I certify that the manuscript represents an original work and that none of the material in the manuscript has been previously published, is included in another manuscript, or is currently under consideration for publication elsewhere, whether in printed form or in electronic media, except that described in the attachment.
In case of acceptance of this text by Demetra: Alimentação, Nutrição & Saude, I declare to be in accordance with the policy of public access and copyright adopted by Demetra, which provides as follows: (a) the authors retain the copyright and grant to the Journal the right of first publication, the work being simultaneously licensed under the Creative Commons Attribution License, which allows the sharing of the work with acknowledgment of authorship and initial publication in this journal; (b) authors are authorized to enter additional contracts separately for non-exclusive distribution of the version of the work published in this journal (eg, publishing in institutional repository or book chapter), with acknowledgment of authorship and initial publication in this journal; and (c) authors are permitted and encouraged to post and distribute their work online (eg, in institutional repositories or on their personal page) at any point before or during the editorial process, as this may lead to productive changes, as well as increase the impact and citation of the published work.
2. Conflict of Interest Statement
I certify that there is no conflict of interest in connection with the submitted article.
Date, signature and full address of all authors.
