Effects of avocado oil supplementation on lipid profile and atherogenic indices in a double-blind and randomised intervention in patients with metabolic syndrome

Authors

  • Ana Carolina Souza Fernandes Azevedo Graduanda em Nutrição; Departamento de Nutrição, Instituto de Ciências Biológicas, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brasil https://orcid.org/0000-0001-8642-8347
  • Mário Flávio Cardoso de Lima Empresa Brasileira de Serviços Hospitalares (EBSERH) / Hospital Universitário da Universidade Federal de Juiz de Fora (HUUFJF); https://orcid.org/0000-0002-5735-4411
  • Erika Lawall Lopes Ramos Mestranda; Programa de Pós-graduação em Saúde, Faculdade de Medicina, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brasil
  • Ana Paula Boroni Moreira Professora; Departamento de Nutrição, Instituto de Ciências Biológicas, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brasil https://orcid.org/0000-0001-5909-1996
  • Claudio Teodoro de Souza Professor Titular; Departamento de Clínica Médica; Faculdade de Medicina, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brasil https://orcid.org/0000-0003-4904-5675

DOI:

https://doi.org/10.12957/demetra.2023.70457

Keywords:

Metabolic Syndrome. Persea. Cholesterol. HDL-Cholesterol. LDL-cholesterol. Triglycerides.

Abstract

Introduction: Metabolic syndrome is defined as a set of clinical conditions that affect approximately 25% of the world’s population and 29.6% of Brazilians. This syndrome is related to increased cardiovascular outcomes, which may be predicted by the lipid profile. Bioactive compounds, such as monounsaturated fatty acids (MUFAs), are strong allies in preventing these outcomes. Avocado is an important food because it contains abundant bioactive compounds and MUFAs. However, few studies evaluated the effects of pure/virgin avocado oil on the lipid profile in humans with metabolic syndrome, and its effects on atherogenic indices are not known. Objective: This study evaluated avocado oil supplementation on lipid levels and atherogenic indices in patients with metabolic syndrome. Method: Thirty-one obese adults were randomised into a control group (soybean oil) and an intervention group (avocado oil). These groups were evaluated in the pre- and post-intervention periods (12 weeks) via clinical anamnesis and nutritional assessment. Results: The control group and the intervention group had higher intakes of lipids and saturated fat than recommended. For the lipid profile and atherogenic indices, no significant difference was observed between the pre- and postintervention periods. Conclusion: These results may have been due to the absence of dietary control, medication overload, intervention duration, mode of administration and dose of the supplement. Therefore, future studies on the effects of avocado oil are needed in this population to better control these variables.

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Author Biography

Mário Flávio Cardoso de Lima, Empresa Brasileira de Serviços Hospitalares (EBSERH) / Hospital Universitário da Universidade Federal de Juiz de Fora (HUUFJF);

Nutricionista da Empresa Brasileira de Serviços Hospitalares (EBSERH) / Hospital Universitário da Universidade Federal de Juiz de Fora (HUUFJF);
Graduação em Nutrição pela Universidade Federal de Goiás (UFG).
Doutorando no grupo de Nutrientes e Exercícios Físicos Aplicados à Síndrome Metabólica (NEFASM) pelo programa de Pós-Graduação em Saúde da Universidade Federal de Juiz de Fora (UFJF);
Mestre em Ciência da Nutrição pela Universidade Federal de Viçosa (UFV);
Especialização em Medicina do Esporte e da Atividade Física pela Universidade Estácio de Sá;
Especialização em Prescrição de Fitoterápicos e Suplementação Nutricional pela Universidade Estácio de Sá;
Especialização em Gestão em Saúde pela Faculdade Educamais;

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Published

2023-02-28

How to Cite

1.
Souza Fernandes Azevedo AC, Cardoso de Lima MF, Lawall Lopes Ramos E, Boroni Moreira AP, Teodoro de Souza C. Effects of avocado oil supplementation on lipid profile and atherogenic indices in a double-blind and randomised intervention in patients with metabolic syndrome. DEMETRA [Internet]. 2023 Feb. 28 [cited 2025 May 1];18:e70457. Available from: https://www.e-publicacoes.uerj.br/demetra/article/view/70457

Issue

Vol. 18 (2023)

Section

Clinical Nutrition

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