Metastatic prostate cancer with negative MRI-targeted prostate biopsies: case report

Authors

  • Victor S. Diniz Departamento de Urologia. Hospital Universitário Pedro Ernesto. Universidade do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil. https://orcid.org/0000-0001-9142-8501
  • Celso M. C. Lara Departamento de Urologia. Hospital Universitário Pedro Ernesto. Universidade do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.
  • Ronaldo Damião Departamento de Urologia. Hospital Universitário Pedro Ernesto. Universidade do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.

DOI:

https://doi.org/10.12957/bjhbs.2022.71660

Keywords:

Prostate Neoplasms, Image-Guided Biopsy, Positron Emission Tomography combined with Computed Tomography, Carcinoma of unknown primary

Abstract

The present article reports a case of an asymptomatic patient with ascending PSA and suspected rectal examination for prostate cancer, who underwent two MRI-targeted prostate biopsies, both being negative for this neoplasm. PSMA PET/CT revealed secondary bone implant and the biopsy of the metastatic lesion showed prostate adenocarcinoma. Docetaxel-based chemotherapy associated with androgen deprivation was performed. Despite the high accuracy of MRI-targeted prostate biopsy, diagnosis can be occasionally difficult and PSMA PET/CT can help to find distant lesions and aid the diagnosis. 

Author Biographies

Victor S. Diniz, Departamento de Urologia. Hospital Universitário Pedro Ernesto. Universidade do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.

Departamento de Urologia. Hospital Universitário Pedro Ernesto. Universidade do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil. 

Celso M. C. Lara, Departamento de Urologia. Hospital Universitário Pedro Ernesto. Universidade do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.

Departamento de Urologia. Hospital Universitário Pedro Ernesto. Universidade do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil. 

Ronaldo Damião, Departamento de Urologia. Hospital Universitário Pedro Ernesto. Universidade do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.

Departamento de Urologia. Hospital Universitário Pedro Ernesto. Universidade do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.

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Published

2022-12-23

How to Cite

Diniz, V. S., Lara, C. M. C., & Damião, R. (2022). Metastatic prostate cancer with negative MRI-targeted prostate biopsies: case report. Brazilian Journal of Health and Biomedical Sciences, 21(2), 146–160. https://doi.org/10.12957/bjhbs.2022.71660

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Section

Clinical Cases