Efeito da suplementação de probióticos no diabetes mellitus: uma revisão sistemática

Alane N. Bezerra, Natália S. Carvalho, Ana Carolina C. Viana, Suelyne R. Morais

Resumo


Devido à importância de se tratar o diabetes mellitus e prevenir suas complicações, o objetivo dessa revisão sistemática foi verificar os efeitos da suplementação de probióticos no tratamento do paciente diabético e sua contribuição na prevenção de suas complicações. Foram utilizadas as plataformas de pesquisa PubMed, Science Direct, Lilacs e Medline. Foram encontrados 11 ensaios clínicos. As principais cepas utilizadas foram dos gêneros Lactobacillus e Bifidobacterium. Os principais efeitos da suplementação de probióticos foram redução estatisticamente significativa da glicemia de jejum, da hemoglobina glicada, da frutosamina e da resistência à insulina, dos níveis séricos de colesterol total e de LDL-C, enquanto o de HDL-C aumentou. A suplementação de probióticos parece melhorar o controle glicêmico e metabólico de pacientes diabéticos.

Descritores: Probióticos; Diabetes Mellitus; Lactobacillus; Suplementação Alimentar; Complicações do Diabetes.


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